Azoxystrobin 18.2% + Difenoconazole 11.4% SC Fungicide Uses

Azoxystrobin 18.2% + Difenoconazole 11.4% SC is a combination, broad-spectrum systemic fungicide registered for use in India under the Insecticides Act, 1968 and sold under various trade names. It pairs a strobilurin (azoxystrobin) with a triazole (difenoconazole), and carries label recommendations across cereals (rice, wheat, maize), cash crops (cotton, turmeric), and vegetables (chilli, tomato, onion), used as a foliar spray against blast, blight, rust, powdery and downy mildew, anthracnose and leaf spots. This active ingredient combination remains legally registered and sold in India; always confirm the current pack label before use. This page lists its mode of action, key benefits and the recommended crop-wise dosage as per manufacturer labels.

Mode of Action

This product combines two fungicides with different, complementary modes of action. Azoxystrobin is a strobilurin (QoI) fungicide that blocks mitochondrial respiration in fungal cells by binding at the Qo site of the cytochrome bc1 enzyme complex, cutting off the fungus's energy (ATP) supply and inhibiting spore germination at a very early stage. Difenoconazole is a triazole (DMI) fungicide that inhibits the C14-demethylase enzyme needed to build ergosterol, an essential component of fungal cell membranes, blocking normal cell membrane formation. Because the two actives interrupt the fungal life cycle at two separate, unrelated biochemical points, the combination gives both preventive and curative activity across a wider range of fungal diseases than either active alone, and is significantly harder for a fungal population to develop resistance against than a single-mode product used repeatedly. Both actives are absorbed into leaf tissue and move within the plant (translaminar and upward/xylem movement), continuing to protect new growth after spraying.

Features & Benefits

• Broad-spectrum, dual-mode systemic control of major fungal diseases — blast, blight, rust, powdery and downy mildew, anthracnose and leaf spots — across cereals, cotton, turmeric and vegetable crops.
• Two complementary, unrelated modes of action reduce the resistance risk compared with using either component alone, and broaden the range of diseases controlled in a single spray.
• Quick uptake with translaminar and upward (xylem) movement within the plant, giving both preventive and curative activity and protecting new growth after application.
• Suitable across a wide range of field, vegetable and fruit crops as a single, broad-spectrum spray.

Recommended Usage of Azoxystrobin 18.2% + Difenoconazole 11.4% SC Fungicide

The table below gives the commonly recommended dose and water volume per acre for each crop and target disease, as listed on manufacturer labels for this active ingredient combination. Always spray in the recommended water volume for uniform coverage, and confirm against the current product label before use.

Doses above (approximately 1 ml per litre of water, i.e. 0.03% spray solution) are the commonly listed formulation-label rates for this combination, rounded to practical spray-tank quantities. Always confirm the current pack label/CIB registration and consult your local agricultural extension office for the latest guidance before use and before harvest.

How to Use

1. Identify your crop and target disease from the table above, and confirm the correct dose per acre for that crop.
2. Measure the required quantity and pre-mix it in a small quantity of water, then add this to the spray tank and top up to the full water volume while stirring, so the suspension concentrate disperses evenly.
3. Spray using a knapsack or power sprayer fitted with a flat-fan or hollow-cone nozzle for uniform leaf coverage, preferably during the early morning or late evening.
4. Avoid spraying in hot, windy conditions or when rain is expected within a few hours, as this reduces efficacy and can cause spray drift or wash-off.
5. Repeat sprays at 10–15 day intervals if disease pressure continues, and always respect the waiting period before harvest; since this product already combines two mode-of-action groups, avoid adding a third fungicide from the same strobilurin or triazole group in the same spray program without good reason.

Precautions & Safety

• Wear appropriate PPE — mask/respirator, gloves, goggles and full-sleeved clothing — while mixing and spraying.
• Do a small jar-compatibility test before tank-mixing with other agrochemicals, and avoid mixing with strongly alkaline materials.
• Store in the original, tightly closed container in a cool, dry place away from direct sunlight, food, feed and out of reach of children and livestock.
• Respect the waiting period (PHI) listed for each crop above before harvesting, and follow your local agricultural extension advice for the latest guidance.
• Even with two modes of action, avoid repeated, back-to-back use of this exact combination on the same crop/disease across a season; rotate with fungicides from genuinely different groups as part of a resistance-management program.
• Wash hands, face and any exposed skin thoroughly with soap and water after handling or spraying, and change out of contaminated clothing before eating, drinking or smoking.